Distinctive High Expression of Antiretroviral APOBEC3 Protein in Mouse Germinal Center B Cells.

Although cultured T cells expressed low levels of mA3 that was increased after LPS stimulation ( Figure 2 C), freshly prepared spleen T cells showed merely background levels of FLAG-tagged mA3 protein expression that reached significantly higher than those in control B6 cells only in non-stimulated homozygotes for the KI allele, but the difference did not reach statistical significance after SRBC stimulation ( Figure 5 C,D).

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