Dosing Colistimethate Every 8 h Results in Higher Plasma Concentrations of Active Colistin Than Every 12-Hourly Dosing without Increase in Nephrotoxicity: A Phase 1 Pharmacokinetics Trial in Healthy Adult Volunteers.

Antibiotics (Basel) · 2022 · PMC9029538 · PMID 35453240

Europe PMC DOI

hedged sentence

0.0500

closest p · 1.0× alpha

0.0500

boldest claim

The sentences

did not reach statistical significancep values > 0.05actually significant

Correlation coefficients did not reach statistical significance (all p values > 0.05), nor were the coefficients nominally high enough to indicate clinically meaningful relationships.

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