Drug Resistance Mechanism of M46I-Mutation-Induced Saquinavir Resistance in HIV-1 Protease Using Molecular Dynamics Simulation and Binding Energy Calculation.

Viruses · 2022 · PMC9031992 · PMID 35458427

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closest p

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quite significantno p-value reported

Up to the 20 ns period, no significant changes between the SASA value of the WT and SQ-WT systems were recorded, but, after that, the difference was quite significant throughout the simulation period.

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