Interferon-γ increases sensitivity to chemotherapy and provides immunotherapy targets in models of metastatic castration-resistant prostate cancer.

With regards to membranous E-cadherin expression in IFNγ-treated groups, PC3-L cells demonstrated a reduction by 43% (p = 0.005), DU-L and PC3-H cells showed small decreases which did not reach statistical significance, while DU-H showed a small, not significant increase (Fig. 2 ).

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