The immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity development.

Sci Adv · 2022 · PMC9045715 · PMID 35476450

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showed a trendno p-value reported

gWAT from B7-H3 KO mice showed a trend toward decreased OCR as compared to WT depot ( Fig. 7D ).

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a slight trendno p-value reported

Consistent with a previous report ( 42 ), we noticed a slight trend toward decreased expression of FAS , SCD1 , and ACLY lipogenic genes in gWAT from B7-H3 KO obese mice as compared to WT lean mice (fig.

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