Gene ontology on the 93 genes reveals the following gene sets that are weakly significant (FDR < 0.01): DNA metabolic process (GO:0006259), heterocycle metabolic process (GO:0046483), and DNA replication (GO:0006260), and MCM10 is identified as one of these early MYCi975 response genes.
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A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression.
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