Salmonella enterica serovar Typhimurium chitinases modulate the intestinal glycome and promote small intestinal invasion.

PLoS Pathog · 2022 · PMC9049507 · PMID 35482787

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Typhimurium strains deficient in only one chitinase showed a trend towards reduced invasion of colonic cells, whereas the strain deficient in both chitinases (Δ STM0233 Δ chiA ) showed a highly significant >70% reduction in invasion compared to WT ( Fig 1B ).

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