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Sphingolipid changes in Parkinson L444P GBA mutation fibroblasts promote α-synuclein aggregation.

Brain · 2022 · PMC9050548 · PMID 35362022

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The per cent of specific sphingolipid species, namely SM, Cer and HexCer, also tended to be higher in PD-GBA fibroblasts, although these changes did not reach statistical significance ( Fig. 3E–G ).

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