A pooled analysis of remote monitoring of CIEDs using one manufacturer’s technology (including IN-TIME) reported that active remote management was associated with a 36% reduction in HFH ( p = 0.007) and a borderline significant reduction in all-cause (but not CV) mortality [ 44 ].
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Digital Technologies to Support Better Outcome and Experience of Care in Patients with Heart Failure.
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Complicated by the COVID-19 pandemic, with huge shifts in patient care patterns during “lockdowns”, the study failed to reach statistical significance overall.
In the DOT-HF (Diagnostic Outcome Trial in Heart Failure) randomised study, an audible alarm was triggered within the device if a threshold of a decreasing trend in transthoracic impedance (reflection of increasing lung water and left ventricular filling pressure) was crossed.