Regarding efficacy, in ION-02 (n = 21), involuntary detrusor contractions on urodynamics at 24 weeks in patients ( P < 0.0508 vs placebo) and average urinary incontinence episodes in the 5000-μg group ( P = 0.0812 vs placebo) showed a trend toward statistical significance.
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Drugs Currently Undergoing Preclinical or Clinical Trials for the Treatment of Overactive Bladder: A Review.
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