Impact of antimicrobial stewardship programs on antibiotic consumption and antimicrobial resistance in four Colombian healthcare institutions.

After the implementation of the ASPs in the general wards of the four healthcare institutions in Colombia, a decreasing trend in the consumption of all antibiotics studied was observed but it only achieved statistical significance for carbapenems.

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Antibiotic consumption and bacterial resistance Prior to the implementation of the ASPs, the four institutions showed a trend towards an increase in broad-spectrum antibiotic consumption (ceftriaxone, cefepime, piperacillin/tazobactam, ertapenem, meropenem, and vancomycin) in general wards and ICUs (Fig. 1 ).

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