High tumor mutational burden predicts worse prognosis for cervical cancer treated with radiotherapy.

The PFS, PRFS, and DMFS rates showed similar a trend toward a worse prognosis for TMB-high patients, although they did not reach statistical significance (Fig. 2 b–d).

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Variables showing P value smaller than 0.25 in univariate analysis were included in subsequent multivariate analysis [ 15 ]; variables that showed borderline significance were also included when they were considered to be clinically relevant, based on the part experience and common sense nature of the model-building strategy [ 16 ].

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