Short pulse and directional thalamic deep brain stimulation have differential effects in parkinsonian and essential tremor.

Sci Rep · 2022 · PMC9068767 · PMID 35508680

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hedged sentences

0.0010

closest p · 0.0× alpha

0.0800

boldest claim

The sentences

highly significantp < 0.001actually significant

ET) revealed a highly significant difference for the factor stimulation condition (ventral contact: F = 113.31, p < 0.001; dorsal contact: F = 62.58, p < 0.001), but no significant interaction between stimulation condition and disease.

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approached significancep = 0.08so close (0.05 < p ≤ 0.1)

This effect was significant for oDBS60 (oDBS60 ventral: PD 19.66% ± 7.2, ET 40.46% ± 22.5, p = 0.0003; oDBS60 dorsal: PD 22.35% ± 7.98, ET 43.28% ± 27.7, p = 0.048) and oDBS30 at the ventral site (oDBS30 ventral: PD 15.86% ± 10.63, ET 31.18% ± 22.64, p = 0.0024, oDBS30 dorsal: PD 16.3% ± 13.0, ET 35.13% ± 26.36, p = 0.16), and approached significance for directional stimulation (dDBS60 dorsal: PD 19.42% ± 12.23, ET 42.24% ± 33.96, p = 0.08) (Fig. 4 A).

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