At univariable analysis, age ( p = 0.136), site of origin ( p = 0.663), and positive margins ( p = 0.479) did not influence CFS, whereas female sex (HR = 2.10, 95% CI 0.90–4.80, p = 0.085) ( Figure 3A ), grade of dysplasia (HR = 2.11, 95% CI 0.92–4.84, p = 0.077), and history of previous OSCC (HR = 2.65, 95% CI 1.18–5.96, p = 0.019) ( Figure 3B ) showed a significant or close-to-significant association.
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Clinical and Histological Prognostic Factors of Recurrence and Malignant Transformation in a Large Series of Oral Potentially Malignant Disorders.
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