nominally significantp = 7.8 × 10 −14
Six signals replicated with Bonferroni correction for multiple testing (p ≤ 0.05/61 = 8.2 × 10 −4 ; Figure 3 B) and we observed 7.2× more nominally significant signals than expected by chance (22 signals; two-sided binomial test: p = 7.8 × 10 −14 ; Figure S3 G).