Survival After Induction Chemotherapy and Chemoradiation Versus Chemoradiation and Adjuvant Chemotherapy for Locally Advanced Rectal Cancer.

23 Also similar to our study, patients treated with systemic chemotherapy before chemoRT had a greater response rate but the difference did not reach statistical significance. 23 The recently published RAPIDO trial found an improved disease-related treatment failure in patients with LARC treated with short-course radiation followed by 4 months of FOLFOX or CAPOX compared with patients treated with chemoRT, TME, and optional adjuvant chemotherapy.

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