CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI: difference from BNP visualized by targeted cGMP biosensors.

Cardiovasc Res · 2022 · PMC9074987 · PMID 33970224

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significanceP = 0.06so close (0.05 < p ≤ 0.1)

The BNP-stimulated cGMP levels did not reach statistical significance from that of CNP stimulation in Sham at the untargeted ( P = 0.06), TnI ( P = 0.09) and AKAP18δ ( P = 0.5) biosensors, but were significantly lower than CNP in HF across all biosensors ( P < 0.005) ( Figure 7D- F ).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.