Sex and chronic stress alter the distribution of glutamate receptors within rat hippocampal CA3 pyramidal cells following oxycodone conditioned place preference.

Neurobiol Stress · 2022 · PMC9076964 · PMID 35535260

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

approaching significancep = 0.06so close (0.05 < p ≤ 0.1)

Two-way ANOVA of large dendrites showed a main effect of sex approaching significance (F 3,224 = 5.81; p = 0.06) and a significant interaction between treatment and condition (F 3,224 = 5.81; p < 0.0001) for the density of GluA1-SIG particles in the cytoplasm in Oxy rats.

also in 2,640 other papers

verged on significanceno p-value reported

Post hoc Tukey showed CIS Oxy-females tended to have a (p = 0.06) greater ratio of GluA1-SIG particles on the plasma membrane of all CA3 dendrites compared to Sal-females, which verged on significance ( Fig. 13 C).

also in 15 other papers

verging on significanceno p-value reported

Statements such as “trending interactions” and “verging on significance” were used to describe data with an alpha of 0.06–0.08.

also in 8 other papers

may be significantno p-value reported

This contrasts with our current study in which Oxy CPP causes redistribution of GluN1 and GluA1 in CA3 spines, which may be significant in regards to increasing excitability and synaptic neuroplasticity.

also in 13,097 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.