All five studies that reported higher doses of NAC 11 – 15) showed a trend pointing toward the reno-protective effect of NAC, with an OR of less than 1.
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N-Acetylcysteine's Renoprotective Effect in Cardiac Surgery: A Systematic Review and Meta-Analysis.
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The sentences
Primary outcome measures Meta-analytic estimate showed a positive trend toward preventing AKI in patients treated with NAC.