Barely Significant
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Insights into the role of electrostatics in temperature adaptation: a comparative study of psychrophilic, mesophilic, and thermophilic subtilisin-like serine proteases.

RSC Adv · 2018 · PMC9085296 · PMID 35547280

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a clear trendno p-value reported
A clear trend is that as the R-SASA value decreases, the desolvation energy penalty paid by the salt bridge increases.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.