Modified Adenosines Sensitize Glioblastoma Cells to Temozolomide by Affecting DNA Methyltransferases.

Front Pharmacol · 2022 · PMC9086827 · PMID 35559231

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did not reach statistical significanceno p-value reported

IPA was able to robustly reduce the enzymatic activity in U251 and T98 cell lines (about 40–45% of inhibition), while in U87 cells, despite the slight decrease, the effect did not reach statistical significance.

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