Except for the ALaCaRT trial, 8 all the included RCTs showed a trend favoring laparoscopic surgery in terms of OS ( Figure 3 B). 2 , 3 , 4 , 8 , 24 , 25 , 26 , 27 , 28 For example, after 10 years of follow-up, the CLASICC trial 3 reported median OS times of 82.7 months (IQR, 67.3-97.6) among the laparoscopic group and 65.8 months (IQR, 49.0-83.8) among the open surgery group.
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Comparison of Survival Among Adults With Rectal Cancer Who Have Undergone Laparoscopic vs Open Surgery: A Meta-analysis.
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