Carboxylesterase-1 Assisted Targeting of HDAC Inhibitors to Mononuclear Myeloid Cells in Inflammatory Bowel Disease.

J Crohns Colitis · 2022 · PMC9089418 · PMID 34633041

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Additionally, the disease activity index [DAI] showed a trend towards improvement in ESM-HDAC528-treated mice [ Figure 6E ] and a reduced colon inflammation histological score was noted after ESM-HDAC528 as compared with controls [ Figure 6F ].

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