near significanceP = 0.07
TOP1 CNA was also associated with TOP1 transcript abundance with near significance (linear regression; P = 0.07) ( Figure 6D ).
TOP1 CNA was also associated with TOP1 transcript abundance with near significance (linear regression; P = 0.07) ( Figure 6D ).
Treatment of 22Rv1 xenograft tumors with the BETi OTX015 or the TOP1i LMP400 resulted in a modest reduction in tumor growth, which did not reach statistical significance.