Barely Significant
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Frataxin deficiency lowers lean mass and triggers the integrated stress response in skeletal muscle.

JCI Insight · 2022 · PMC9090249 · PMID 35531957

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difference was apparentno p-value reported
Yet, exercise training had no effect on muscle mass in TG mice, even though the exercise intervention was started before a BW (and presumably, muscle mass) difference was apparent in TG mice.

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