Env-independent protection of intrarectal SIV challenge by vaccine induction of Gag/Vif-specific CD8<sup>+</sup> T cells but not CD4<sup>+</sup> T cells.

Mol Ther · 2022 · PMC9092394 · PMID 35231604

Europe PMC DOI

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did not reach statistical significanceno p-value reported

While these results did not reach statistical significance and were obtained in Mamu-B∗08 -positive animals, they suggest that, under certain circumstances, vaccine-induced CD8 + T cells may provide sterilizing immunity.

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