Barely Significant
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An Antibiotic-Loaded Hydrogel Demonstrates Efficacy as Prophylaxis and Treatment in a Large Animal Model of Orthopaedic Device-Related Infection.

Front Cell Infect Microbiol · 2022 · PMC9093643 · PMID 35573772

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quite significantno p-value reported
The burden to the patient can be quite significant, and in order to minimise this burden there is increasing trend towards single stage revision surgery in appropriately selected patients ( Gehrke et al., 2013 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.