Gabapentin and pregabalin in bipolar disorder, anxiety states, and insomnia: Systematic review, meta-analysis, and rationale.

Mol Psychiatry · 2022 · PMC9095464 · PMID 34819636

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showed a trendno p-value reported

Compared to placebo, pregabalin significantly reduced the RR of drop-out due to inefficacy (RR 0.44, 95% CI 0.28 to 0.70), but showed a trend increase in RR of drop-out due to adverse events (RR 1.30, 95% CI 0.99–1.71) (Supplementary Appendix, Fig. 21 ).

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