The effect of TLR-4 on the proliferation and differentiation of bone mesenchymal stem cells and its relationship with the Wnt signal transduction pathway during bone nonunion.

Ann Transl Med · 2022 · PMC9096412 · PMID 35571435

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showed a trendno p-value reported

The results showed that the mRNA expression levels of TLR-3 and TLR-4 in the bone nonunion group were much higher than those in the control group, and the expression of TLR-3 showed a trend of increasing first and then decreasing, while the expression of TLR-4 increased over the whole period ( Figure 2A ).

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