Presence and Implications of Anti-Angiotensin Converting Enzyme-2 Immunoglobulin M Antibodies in Anti-Melanoma-Differentiation-Associated 5 Dermatomyositis.

Compared with the anti‐ACE2‐IgM‐negative group, patients with anti‐ACE2 IgM antibodies were more likely to receive pulse dose methylprednisolone (80% vs 30%, P = 0.043) and showed a trend toward higher prevalence of synovitis (100% vs 51%, P = 0.059) and worse FVC (median FVC percentage predicted 59% [interquartile range (IQR) 58‐61] vs 78% [IQR 63‐93], P = 0.056) (Table 1 ).

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