Boosting nutrient starvation-dominated cancer therapy through curcumin-augmented mitochondrial Ca²⁺ overload and obatoclax-mediated autophagy inhibition as supported by a novel nano-modulator GO-Alg@CaP/CO.

1 H, I, the glucose content and pH value demonstrated a clear trend of decreasing with time extended, revealing the successful conversion of glucose into gluconic acid together with pH value dropped from ~ 7.4 to ~ 3.0 and glucose decrease from 1 to ~ 0.4 mg/mL, respectively.

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