Response to Treatment with Melatonin and Clonazepam versus Placebo in Patients with Burning Mouth Syndrome.

In the clonazepam group, the score decreased from 8.8 ± 1.2 to 5.5 ± 3.6 ( p < 0.01), and in the placebo group, the score decreased from 8.1 ± 1.8 to 7.7 ± 1.9, though in this case, the difference failed to reach statistical significance ( p > 0.05).

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There were no significant differences between the first and second visits in any group, though the clonazepam group showed values very close to statistical significance ( p = 0.055).

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