Unraveling the Molecular Basis of the Dystrophic Process in Limb-Girdle Muscular Dystrophy LGMD-R12 by Differential Gene Expression Profiles in Diseased and Healthy Muscles.

Cells · 2022 · PMC9104122 · PMID 35563815

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Interestingly, the LGMD-R12 disease-causing gene ANO5 ranked in the top 0.1% of most downregulated genes, whereas other anoctamin genes showed a trend to being slightly upregulated ( ANO3, ANO7, ANO9, ANO7L1 ) ( Figure 3 A).

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