TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS-CoV-2 infection.

EMBO J · 2022 · PMC9108609 · PMID 35178710

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showed a trendno p-value reported

However, TLR7 knockout completely abolished type I IFNα and showed a trend toward impaired CXCL10 production in response to SARS‐CoV‐2 exposure, as compared to AAVS1 KO control pDCs (Fig 5 B–E).

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