Although the analysis did not reach statistical significance (p=0.078 for RV/TLC) and thus could not provide any further corroborating evidence for our hypothesis, the analysis did suggest that a substantial proportion (36%) of air trapping effect on exercise capacity may be mediated through stroke volume.
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Remote exposure to secondhand tobacco smoke is associated with lower exercise capacity through effects on oxygen pulse, a proxy of cardiac stroke volume.
2
0.0780
0.0790
The sentences
marginally significantp≤0.079
Furthermore, baseline respiratory symptoms were significantly associated with FRC/TLC with more air trapping being associated with higher likelihood of having respiratory symptoms at baseline (RV/TLC association was marginally significant; p≤0.079).