A dual conditional CRISPR-Cas9 system to activate gene editing and reduce off-target effects in human stem cells.

Mol Ther Nucleic Acids · 2022 · PMC9112054 · PMID 35615005

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did not reach statistical significanceno p-value reported

If only doxycycline was used without Shield1, there seemed to be a slight decrease in firefly luciferase activity, but this decrease did not reach statistical significance ( Figure 3 C).

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