Palmitoylated prolactin-releasing peptide treatment had neuroprotective but not anti-obesity effect in fa/fa rats with leptin signaling disturbances.

Nutr Diabetes · 2022 · PMC9119973 · PMID 35589696

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showed a trendno p-value reported

The fa/fa saline group showed a trend toward a decrease in phosphoinositide 3-kinases (PI3K), pAkt (Ser473), and pGSK-3β (Ser9) levels and a significantly lower pAkt (Thr308) level compared to the control saline group suggesting IR in the hippocampus.

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