Barely Significant
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Proteomic characterization of post-mortem human brain tissue following ultracentrifugation-based subcellular fractionation.

Brain Commun · 2022 · PMC9123841 · PMID 35611312

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1
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0.0700
closest p · 1.4× alpha
0.0700
boldest claim

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showed a trendP = 0.07so close (0.05 < p ≤ 0.1)
The mean Manders M2 coefficient was calculated for each subject, and Student’s t -test showed a trend ( T = −2.18, P = 0.07) towards increased overlap of GSK3β signal with nuclear staining in Control versus Alzheimer’s disease ( Fig. 4C ), providing likely validation of the mass spectrometry results.

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