The transmembrane domain of the amyloid precursor protein is required for antiamyloidogenic processing by α-secretase ADAM10.

J Biol Chem · 2022 · PMC9127328 · PMID 35398353

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showed a trendno p-value reported

In the cross-linking assay, like APP-TMS, variants APP(↔628–630) and APP(↔634–639) did not coaggregate, whereas APP(↔641–644/646) showed a trend toward an increase in PCC ( Fig.

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