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An eIF3d-dependent switch regulates HCMV replication by remodeling the infected cell translation landscape to mimic chronic ER stress.

Cell Rep · 2022 · PMC9127984 · PMID 35508137

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Notably, virus DNA levels were reduced by less than 30% in HCMV-infected NHDFs treated with eIF3d-siRNA compared to control, non-silencing siRNA, and this difference (p > 0.05) did not reach statistical significance ( Figure 2E ).

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