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MicroRNA-503 Exacerbates Myocardial Ischemia/Reperfusion Injury via Inhibiting PI3K/Akt- and STAT3-Dependent Prosurvival Signaling Pathways.

Oxid Med Cell Longev · 2022 · PMC9130001 · PMID 35620576

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Also, p-Akt (T450) and p-Akt (T308) were decreased significantly in the H/R+NC group compared with the Con+NC group (Figures 6(d) and 6(e) ), p-Akt (T450) was further decreased by Agomir-503 treatment under both normoxia and H/R conditions, and Agomir-503 also tended to further decrease p-Akt (T308) under H/R condition, but the difference did not reach statistical significance ( Figure 6(e) ).

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