CFTR targeted therapies: recent advances in cystic fibrosis and possibilities in other diseases of the airways.

Eur Respir Rev · 2020 · PMC9131734 · PMID 32554756

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showed a trendno p-value reported

A recently completed pilot study evaluating ivacaftor in COPD patients with chronic bronchitis showed a trend towards improved symptoms and sweat chloride levels, as well as a ∼20% improvement in CFTR activity, with no safety concerns noted [ 120 ].

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