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Chronic treatment with serelaxin mitigates adverse remodeling in a murine model of ischemic heart failure and modulates bioactive sphingolipid signaling.

Sci Rep · 2022 · PMC9132995 · PMID 35614179

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While modest increases in sphingosine, dihydrosphingosine (DHSo) and dihydro S1P (DHS1P) were also noted, differences between the groups failed to reach statistical significance.

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