Protposer: The web server that readily proposes protein stabilizing mutations with high PPV.

While the eSR in Protposer is not directly related to the ΔΔG values of the mutations used for training, higher eSR threshold values lead to higher PPVs, and there is a clear trend indicating that, as the PPV increases, the mean experimental ΔΔG value increases as well ( Fig. 4 D).

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