While the difference did not reach statistical significance in this study, it may be clinically important as total piperacillin clearance in the CVVHDF group was 7.5 (5.9–11.2) L/h, compared to 4.7 (4.5–9.6) L/h in the CVVH group ( p = 0.21) ( 44 ).
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Antimicrobial Dosing Recommendations in Pediatric Continuous Renal Replacement Therapy: A Critical Appraisal of Current Evidence.
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