Conversely, the ECOG PS (HR = 3.0, 95% CI 0.9–9.6, p = 0.070) and the MGMT status (HR = 2.1, 95% CI 0.9–5.0, p = 0.075) did not reach statistical significance ( Table 4 ).
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Newly Diagnosed Multifocal GBM: A Monocentric Experience and Literature Review.
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Particularly in the multivariate analysis for OS, MGMT status had a strong tendency towards statistical significance, suggesting its role as an independent prognostic indicator, as shown in other studies [ 10 , 15 ].