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Chimeric Virus-like Particle-Based COVID-19 Vaccine Confers Strong Protection against SARS-CoV-2 Viremia in K18-hACE2 Mice.

Vaccines (Basel) · 2022 · PMC9143195 · PMID 35632541

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A trend toward a lower viral load was observed in the nasal turbinates and trachea, but the differences did not reach statistical significance.

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a slight trendno p-value reported
While there was a slight trend toward viral load reduction in the lower respiratory tract, the effect of vaccination on the viremia suppression was considerable.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.