Overview of Recent Liquid Chromatography Mass Spectrometry-Based Methods for Natural Toxins Detection in Food Products.

A total of 1966 papers were published in the selected period with a positive trend over the years and with mycotoxins representing the most abundant class ( n = 1122), followed by alkaloids ( n = 459), marine toxins ( n = 244), and to a lesser extent glycoalkaloids ( n = 22), furocoumarins ( n = 10) and cyanogenic glycosides ( n = 9) ( Figure 2 ).

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Recently, a clear trend in this sector is towards the development of new LC-MS methods capable of monitoring molecules showing different physicochemical properties, as in the case of natural toxins belonging to different classes, multicontaminants or multianalytes (e.g., bioactive compounds).

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