Perinatal Obesity Induces Hepatic Growth Restriction with Increased DNA Damage Response, Senescence, and Dysregulated Igf-1-Akt-Foxo1 Signaling in Male Offspring of Obese Mice.

Int J Mol Sci · 2022 · PMC9144113 · PMID 35628414

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a marked trendno p-value reported

Immunofluorescent staining supported this finding showing a marked trend of higher p21 intensity in livers of HFD than in livers of SD offspring ( Figure 5 B,C).

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