Inflammatory Gene Expression Associates with Hepatitis B Virus cccDNA- but Not Integrant-Derived Transcripts in HBeAg Negative Disease.

Viruses · 2022 · PMC9146050 · PMID 35632812

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Stratifying biopsies according to their frequency of HBsAg pos hepatocytes (0 = negative; 1 <33%; 2 = 33–66% and 3 >66% HBsAg pos hepatocytes) showed a trend towards preS1/S2 RNA levels associating with higher HBsAg scores independent of disease stage ( Figure 4 B).

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